GenuIN Biotech utilizes its proprietary ShGE™ gene silencing platform to generate a validated series of gene-silenced cell lines. These cell lines stably express short hairpin RNA (shRNA) targeting specific genes and cover common tumor cell lines (strains), meeting your research needs for various diseases and biological regulatory mechanisms. Our gene-silenced cell lysates are validated by immunoblotting and offer advantages such as stable quality, ease of use, and affordability.
Lentivirus-mediated shRNA integration into chromosomes, combined with puromycin selection, allows for KD cell purity reaching up to 100%. Gene silencing efficacy is validated at the mRNA or protein level. Wild-type (WT) and gene-silenced (KD) cell lysates are provided simultaneously for your convenience in comparative experiments.
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